high PSA reading 6 weeks post OP

User

Posted 01 Sep 2020 at 12:47

8.3ug/L is the same as 8.3ng/mL - too high for someone with no prostate. You are speaking to the surgeon this week anyway and s/he may be able to explain the high PSA in the context of your pathology. If not offered, request an immediate referral to oncology but I would hope that the surgeon or GP will be contacting the lab to check your results haven't been mixed up with someone else's.

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User

Posted 01 Sep 2020 at 13:47

The level should be <0.1 max. Thats the threshold for being proactive. Ideally you should be discussing this your urology consultant who would make the call on referral.

User

Posted 01 Sep 2020 at 15:43

Technically, <0.2 - that's the actual threshold in the NICE guidelines. For biochemical recurrence, they use 0.2 or three successive rises over 0.1.

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User

Posted 02 Sep 2020 at 14:19

Just to update you all. Had my telephone consultation and Histology. Cancer had gone to the seminal vesicles, but still all organ contained with negative margins, but cancer upgraded from Gleason 7 to Gleason 9, so more aggressive than the biopsy suggested. Consultant wants a CT and Bone scan and a repeat of my PSA test in 2 weeks to check it wasn't a red herring. He says infection can interfere with PSA but not to the extent of my reading.

Ian

User

Posted 02 Sep 2020 at 14:44

Hi Ian,

If he sends the form for you to have a psa test I don't suppose you need to wait 2 weeks. Although perhaps he's thinking any effects from the UTI or anything else might have declined by then.

It's common to have Gleason upgraded, mine was upgraded to 4+4. A nine could be 4+5 or 5+4. The former being marginally better.

Negative margins is good although I don't know how that squares with seminal vesicle involvement. Perhaps someone else will comment.

Carry on hoping the reading is an error. I had one strange test which I got retested to get the right result. Although the odd test was at another lab and they advise you to use the same lab.

All the best,
Peter

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