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My dad has been diagnosed at the age of 58

User
Posted 16 Sep 2019 at 21:35

I was diagnosed and confirmed with Aggressive Prostate Cancer T3 Gleason scale was either 5-4 or 4-5 cannot remember which way round on 19/12/14.

From that point on everything happened very quick and efficiently at my Local Hospital which has always been outstanding and that of the Christie in Manchester, it started with my first injection of Zoladex 10.8 Jan 15 which continued with a new injection every 12 weeks for 2 years finishing Jan17.

The rationale for this HRT is this, Testosterone feeds the cancer in the prostate, so the way to shut that down is to give it female hormones it also over a short period reduces the swelling of the cancer itself making it simply a smaller target to deal with in my case this was 20 sessions of Radiotherapy which started 15 Apr 15, this so this explains why there is a short time delay from first HRT injection to 1st session of Radiotherapy, to allow the testosterone to stop and to hopefully reduce the prostate gland in size for it to be zapped more accurately and efficiently by the machine, my last of my 20 sessions finished 130515, which was when I rang the bell, wow what a great feeling.

Here I am nearly 5 years down the line with a PSA of 0.02 as at Jul 19, So the message is very clear No one knows your body better than yourself and you know when something is wrong and you know when something is so unusual you know you need to see the Doctor I was diagnosed with aggressive yes , but I reacted quickly and here I am 5 years later, had I left it, it might have been a different outcome.

IMO there has only been 2 down sides to all of this 1) first rear internal is a little unnerving to Mr Macho man, and 2) after 2 year of female HRT as it were I developed a little more than man boobs in fact a little more than that, but you will find it very very easy to live with these tiny 2 downsides, when you consider the alternative.

To all keep your chins up we have the best Medical Staff, the Best Equipment, giving us the best chance there is, no one can ask more than that, and when you ring that Bell !!! you suddenly realise this after all that you have been through, and the care carries on from there.

Edited by member 16 Sep 2019 at 21:44  | Reason: Not specified

User
Posted 16 Sep 2019 at 22:41

Originally Posted by: Online Community Member
The rationale for this HRT is this, Testosterone feeds the cancer in the prostate, so the way to shut that down is to give it female hormones it also over a short period reduces the swelling of the cancer itself making it simply a smaller target to deal with in my case this was 20 sessions of Radiotherapy which started 15 Apr 15, this so this explains why there is a short time delay from first HRT injection to 1st session of Radiotherapy, to allow the testosterone to stop and to hopefully reduce the prostate gland in size for it to be zapped more accurately and efficiently by the machine, my last of my 20 sessions finished 130515, which was when I rang the bell, wow what a great feeling.

You weren't on HRT or female hormones.

Zoladex prevents your body from producing testosterone.

Lack of testosterone will shrink the prostate, but that's not the main reason it's used here. It's used to prevent prostate cells growing. Then when they are hit with radiation, they are less able to recover, and it increases the chance of wiping out all the cancer. It's a kind of double-whammy, which makes the treatment more effective.

All men normally have some estrogen as well as testosterone. Estrogen will cause breast growth, but the testosterone prevents breast growth. Take the testosterone away, and then the estrogen dominates (in some men) and causes breast growth. This can be prevented by taking Tamoxifen, or getting a single RT blast to the breast buds early on.

 
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