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Psa rise

User
Posted 11 Feb 2016 at 10:40

It isn't a popular thing to write on here but the trial data showed that if Abbi fails then Enza will also fail, and vice versa. That is why NICE made the decision not to allow both ( as quoted above). There are people who find it hard to believe or accept, because Abbi and Enza work in very different ways but generally, the most important thing at that stage is for the oncologist to use all the information about a man's disease behaviour, progression, what worked well or not, etc to judge whether Abbi or Enza is going to be the best bet.

There are men on here who fought for one after the other, but I suspect this is an emotional rather than rational response ... the idea that there were two drugs to try and then suddenly the option of both was ripped away rather than any evidence that it would extend their life. Or perhaps not everyone reads the trial reports.

Alathays continues to campaign for it in Ireland but his disease is so atypical it would probably be worth the fight in his case!

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard
User
Posted 11 Feb 2016 at 17:46

My understanding is the same as Lyn's.

The reason I'll be glad if Auld Codger is right is as follows.

I'm on Enzo. Sometime it will cease to be effective. My next stop is then likely to be chemo. Once I've had chemo, maybe just maybe, Abi could then be effective.

User
Posted 11 Feb 2016 at 19:09

Originally Posted by: Online Community Member
Hoping that my cancer is suitable for trial drug as its a 3rd stage trial and sounds reasonably promising. The drug is called galeterone but I have to have a cancer mutation called AR-V7 (sounds like a Blakes 7 character to me !). So now it's wait to see if I have that mutation otherwise no trials available for advanced PC if you have had docetaxl.
Therefore abbi or enzo only. Not saying the above is gospel but marsden quack said 4 hours ago.


Kev - your Onco knows best but, just in case he might of missed something, check these two out:


http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-of-vt464-for-men-with-prostate-cancer-that-is-no-longer-controlled-with-hormone-therapy#undefined


http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-of-olaparib-for-prostate-cancer-that-has-spread-and-got-worse-despite-hormone-therapy-and-chemotherapy-toparp


 Edit


VT464 is not for people who have had chemo. My bad.

Edited by member 11 Feb 2016 at 19:15  | Reason: Not specified

 
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